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Publications / Natural Products with Potential for the Treatment of Pain: Global Evidence from the NAPRALERT Database >

Access: 10.1021/acs.jnatprod.4c00439
authors James G. Graham ORCID , Jonathan Bisson ORCID , Guy H. Harris , Zaijie Jim Wang , Donald P. Waller , Guido F. Pauli ORCID
journal Journal of Natural Products
subjects Natural products Pain management NAPRALERT Drug discovery Ethnomedicine Database analysis
Natural products (NPs) continue to inform the discovery and development of a diversity of drugs, both marketed and investigational. Pain, one of the most common of human experiences and profound challenges in medicine and biology, has emerged at the core of an urgent societal problem, in the United States and globally. The present study employs a retrospective analysis of an extensive set of published literature curated in the NAPRALERT database to identify NPs with experimental evidence of bioactivity supporting the selection and prioritization of NP leads with promise in pain management.
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